OTSC® suggested for first-line treatment for bleeding
We’re excited to announce important news in endoscopic bleeding management. The new ESGE guideline on bleeding management1 has been published and it marks a significant moment for evidence-based endoscopic care:
OTSC® is suggested for first-line treatment for bleeding.
Here’s what makes this update particularly noteworthy:
- Exclusive recognition of OTSC® data among cap-based clips
- The recommendation is built on a foundation of RCT evidence by Schmidt et al., Jensen et al., Maier et al., Chan et al., Lau et al. and Soriani et al. – all based exclusively on OTSC® technology
- The guideline acknowledges the cost-effectiveness of OTSC®, particularly in first-line use
A big congratulations to Prof. Gralnek, his co-authors, and the entire ESGE team on this important update.
One point close to our hearts: the guideline’s emphasis on training as the foundation of safe and effective application. It’s something we’ve been committed to from day one and we are genuinely delighted to see it find its place in a landmark guideline like this.
Take the next step towards guideline-compliant practice: book a training and make sure your team has the skills and confidence to apply OTSC® safely from day one. Get in touch with us to schedule your training!
Want to learn more about OTSC®? Find all the information on our website:
https://ovesco.com/otsc-system/
https://ovesco.com/otscneo-system/
1 The ESGE Guideline Update 2026 suggests the use of OTSC® as monotherapy as an alternative to combination therapy for the first-line endoscopic treatment of peptic ulcer bleeding with Forrest Ia/Ib stigmata,due to a lower risk of further bleeding compared with standard endoscopic hemostasis therapy. This is a conditional recommendation based upon very low quality evidence. Please refer to the full ESGE Guideline Update 2026 for complete recommendations, indications, limitations, and supporting evidence.
Gralnek IM, Morris J, Laursen SB, Camus M, Tziatzios G, Debels LK, Nigam GB, Erőss B, Goetz M, Forbes N, Cúrdia Gonçalves T, Kurek K, Bretthauer M, Tham TC. Endoscopy. 2026 May 22. Epub ahead of print. doi:10.1055/a-2863-8314.
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