FTRD® System for rNETs – Study shows high R0 rates and short procedure times

Multicenter study with the FTRD® demonstrates high R0 resection rates, no recurrences, and short procedure times for rectal neuroendocrine tumors (rNETs)

Key findings

• 73/114 cases with rNET in the EFTR resection specimen
• 97.3% R0 resection (71/73)
• Zero recurrence over median 13 months follow-up
  (endoscopic follow-up was available for 84 of 114 patients (73.7%))
• Only minor complications (10 cases of minor post-operative bleeding (8.8%), 1 case of post-procedural pain (0.9%))

Study details

• Multicenter retrospective analysis at 11 medical centers in the Netherlands and Germany (02/2016 – 10/2024)
• 114 patients with rNETs (38% female; median age 56 years)
• Aim: Assessment of the efficacy and safety of endoscopic full-thickness resection (EFTR) using the FTRD® System in the treatment of rNETs
• Median size of NETs: 6 mm
• Median procedure duration: 25 min

Stathopoulos P, Probst A, Messmann H, Brand M, Weich A, Wannhoff A, Caca K, Koutsoumpas A, Tribonias G, Mende M, Textor M, Kouladouros K, Paspartis G, Denzer UW; in cooperation with the “Dutch eFTR Working Group”: Albers SC, Bastiaansen, de Wijkerslooth TR, van der Spek BW, Schreuder R-M, Seerden TCJ. Effektivität und Sicherheit der endoskopischen Vollwandresektion (eFTR) bei neuroendokrinen Tumoren des Rektums (rNET) mit dem FTRD: Multizentrische, retrospektive Studie / Effectiveness and safety of endoscopic full-thickness resection (eFTR) for rectal neuroendocrine tumors (rNET) using the FTRD: A multicenter, retrospective study. Presentation at Viszeral Medizin (DGVS) 2025 (18 Sep), Leipzig, Germany.

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