87.9 % R0-resection of non-lifting and submucosal colonic lesions with FTRD®
Aepli P et al., Gastroenterology and Hepatology Unit, Luzerner Kantonsspital, Lucerne, Switzerland, and Division of Gastroenterology/Hepatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, reported on the clinical experience of the two tertiary referral centers with FTRD procedures.
33 consecutive patients with colonic neoplasms (21 colon, 12 rectum) were scheduled for EFTR using the FTRD device between 05/2015 and 11/2016. Indications were residual adenoma with non-lifting sign after previous polypectomy (n=18), non-lifting adenoma without previous polypectomy (n=4), staging following resection of a malignant polyp (n=4), adenoma at appendiceal orifice (n=2), primary EFTR of polyps suspected to be malignant (n=2), adenoma involving a diverticulum (n=1), non-lifting adenoma recurrence after EFTR (n=1), and incomplete resection of neuroendocrine tumor G1 (n=1).
31 resections were successfully performed. In one case the target lesion could not be reached because of sigmoid stenosis due to diverticulosis, the other failure was due to snare malfunction.
Resection was en bloc and histologically complete (R0) in 87.9 % (29/33) of patients. The mean diameter of resected specimen as assessed by the pathologist was 2.7 cm (range 18-43 mm). Three post-procedure bleedings and one perforation were seen.
The authors concluded that the FTRD System offers an additional endoscopic approach in the management of non-lifting colorectal lesions and helps to avoid surgical interventions.
Endoscopic full thickness resection (EFTR) of colorectal neoplasms with the Full Thickness Resection Device (FTRD): Clinical experience from two tertiary referral centers in Switzerland
Aepli P, Criblez D, Baumeler S, Borovicka J, Frei R (2017)
United European Gastroenterology Journal 0(0) 1-8